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Bacillus subtilis strains form bacitracin and ampicillin for sale online. Pseudomonas aeruginosa has the ability to form some types of pyocompounds (pyocinase, pyocyanin, etc.). Bacillus brevis forms gramicidin and tyrothricin. Bacillus subtilis produces some polypeptide antibiotics. Bacillus polimixa forms polymyxin (aerosporin). Actinomycetes are fungal-like bacteria. More than 200 antimicrobial compounds of antibacterial, antiviral and antifungal orientation have been obtained from actinomycetes. The most famous of them: streptomycin, tetracycline, erythromycin, neomycin, etc.

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Streptomyces aureofaciens secrete chlortetracycline and tetracycline.
Streptomyces griseus forms streptomycin, mannosidostreptomycin, cycloheximide and streptocin.
The most important manufacturers of antibiotics. Fungi produce cephalosporin
Penicillium notatum and Penicillium chrysogenum form penicillin.

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Aspergillus flavus forms penicillin and aspergillic acid. Aspergillus fumigatus forms fumigatin, spinulosin, fumigacin (gelvolic acid) and gliotoxin. Rice. 3. The photo shows a colony of hay bacillus - soil bacteria. Bacillus subtilis produces some polypeptide antibiotics.

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The staining of bacterial cells in different colors depending on the thickness of the cell was invented in 1884 by the Danish bacteriologist Hans Christian Joachim Gram. His staining method played a major role in the development of the classification of bacteria.

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Antibiotics are capable of producing some strains of bacteria, fungi, and actinomycetes. ampicillin, the strains of Penicillium notatum and Penicillium chrysogenum form penicillin. In the photo, the structure of the bacterial wall of gram-positive (right) and gram-negative (left) bacteria.

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In bacteria, which, when stained according to Gram, acquire a red or pink color (gram-negative), the cell wall is thick, multilayered.

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The outer membrane of gram-negative bacteria serves as protection against some antibiotics - lysozyme and penicillin.

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In addition, the lipid part of the outer sheet of the membrane of these bacteria plays the role of endotoxins, which, entering the bloodstream during infection, cause powerful intoxication and toxic shock.

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Bacterial cells, which, when stained according to Gram, acquire a violet color (gram-positive), the cell wall is thin. The outer sheet of the membrane is devoid of a lipid layer - protection from adverse conditions. Such bacteria are easily damaged by bacteriostatic antibiotics and antiseptics.
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Rice. 7. The photo shows a smear stained according to Gram. Blue gram-positive cocci and pink gram-negative bacilli are visible. There are the following groups of antibiotics, differing in chemical composition:
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Beta-lactam antibiotics. Tetracycline and its derivatives. Aminoglycosides and aminoglycoside antibiotics. Macrolides. Levomycetin. Rifampicins. Polyene antibiotics. back to content Read Article
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